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Eukaryot Cell. 2006 Jul;5(7):1169-73.

Plasmodium falciparum AMA1 binds a rhoptry neck protein homologous to TgRON4, a component of the moving junction in Toxoplasma gondii.

Author information

1
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California 94305-5124, USA.

Abstract

Plasmodium falciparum apical membrane antigen 1 (PfAMA1) coimmunoprecipitates with the Plasmodium homologue of TgRON4, a secreted rhoptry neck protein of Toxoplasma gondii that migrates at the moving junction in association with TgAMA1 during invasion. PfRON4 also originates in the rhoptry necks, suggesting that this unusual collaboration of micronemes and rhoptries is a conserved feature of Apicomplexa.

PMID:
16835460
PMCID:
PMC1489286
DOI:
10.1128/EC.00040-06
[Indexed for MEDLINE]
Free PMC Article

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