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Antiviral Res. 2006 Sep;71(2-3):181-91. Epub 2006 Jun 23.

Papillomavirus and treatment.

Author information

1
Rega Institute for Medical Research, K.U. Leuven, Belgium. robert.snoeck@rega.kuleuven.ac.be

Abstract

Human papillomaviruses (HPVs) are small DNA viruses responsible for a broad range of clinical presentations, characterized histologically by the proliferation of epithelial cells. HPVs are responsible for benign as well as malignant lesions, the most frequent of the latter being cervical carcinoma. A better knowledge of the immunobiology of these lesions allowed the development of prophylactic vaccines (for the most frequent genital types) that are presently under evaluation. The present paper describes different approaches for the treatment of HPV lesions, still mostly based on surgery, and underlines the importance of developing adjuvant therapies.

PMID:
16831473
DOI:
10.1016/j.antiviral.2006.06.007
[Indexed for MEDLINE]
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