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Orig Life Evol Biosph. 2007 Feb;37(1):47-54. Epub 2006 Jul 5.

Condensation of amino acids to form peptides in aqueous solution induced by the oxidation of sulfur(iv): an oxidative model for prebiotic peptide formation.

Author information

1
Department of Chemistry, The University of Hong Kong, Pokfulam Road, Hong Kong, P. R. China. yangdan@hku.hk

Abstract

Condensation of amino acids to peptides is an important step during the origin of life. However, up to now, successful explanations for plausible prebiotic peptide formation pathways have been limited. Here we report that the oxidation of sulfur (IV) can induce the condensation reaction of carboxylic acids and amines to form amides, and the condensation reaction of amino acids to form peptides. This might be a general reaction contributing to prebiotic peptide formation.

PMID:
16821097
DOI:
10.1007/s11084-006-9012-y
[Indexed for MEDLINE]

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