Format

Send to

Choose Destination
J Bioinform Comput Biol. 2006 Apr;4(2):357-72.

Analysis of conserved hydrophobic cores in proteins and supramolecular complexes.

Author information

1
Gamaleya Institute of Epidemiology and Microbiology, Gamaleya Str. 18, Moscow 123098, Russia. akaryagina@rambler.ru

Abstract

The conserved hydrophobic core is an important feature of a family of protein domains. We suggest a procedure for finding and the analysis of conserved hydrophobic cores. The procedure is based on using an original program called CluD (http://monkey.belozersky.msu.ru/CluD/cgi-bin/hftri.pl). Conserved hydrophobic cores of several families including homeodomains and interlock-containing domains are described. Hydrophobic clusters on some protein-DNA and protein-protein interfaces were also analyzed.

PMID:
16819788
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center