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J Bacteriol. 2006 Jul;188(14):5289-92.

Regulation of the Chlamydia trachomatis histone H1-like protein Hc2 is IspE dependent and IhtA independent.

Author information

1
Host-Parasite Interactions Section, Laboratory of Intracellular Parasites, NIAID, NIH, Rocky Mountain Laboratories, Hamilton, MT 59840, USA.

Abstract

The chlamydial histone-like proteins, Hc1 and Hc2, function as global regulators of chromatin structure and gene expression. Hc1 and Hc2 expression and activity are developmentally regulated. A small metabolite that disrupts Hc1 interaction with DNA also disrupts Hc2 interactions; however, the small regulatory RNA that inhibits Hc1 translation is specific to Hc1.

PMID:
16816202
PMCID:
PMC1539943
DOI:
10.1128/JB.00526-06
[Indexed for MEDLINE]
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