The contribution of the response-reinforcer dependency to the control of behavior was investigated. Pigeons were trained to key peck under a variable-interval schedule of reinforcement. With the total number and temporal distribution of reinforcer deliveries in experimental sessions constant, the effects of varying the percentage of response-independent reinforcement were examined. At different times, 100%, 66%, 33%, 10%, or 0% of the scheduled reinforcers were delivered dependent upon key pecking and the remainder were delivered independently of responding. Response rates were related to the percentage of response-dependent reinforcement with lower response rates associated with smaller percentages of response-dependent reinforcement. The results suggest that the response-reinforcer relation exerts control over behavior in a manner similar to that exerted by other parameters of reinforcement.