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Clin Infect Dis. 2006 Aug 1;43(3):377-80. Epub 2006 Jun 20.

HIV type 1 RNA level as a clinical indicator of renal pathology in HIV-infected patients.

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Department of Medicine, Division of Nephrology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.


To determine the value of human immunodeficiency virus type 1 (HIV-1) RNA level in distinguishing HIV-associated nephropathy from non-HIV-associated nephropathy renal pathological conditions, we retrospectively compared renal histopathological findings for 86 HIV-infected patients according to HIV-1 RNA levels. We found that HIV-associated nephropathy was unlikely among patients with HIV-1 RNA levels <400 copies/mL. Hypertensive vascular disease surpassed HIV-associated nephropathy as the most common renal pathological finding among the entire cohort. HIV-1 RNA level did not correlate with renal survival.

[Indexed for MEDLINE]

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