Live viral vaccines in a DiGeorge syndrome patient

Arch Dis Child. 2007 Jun;92(6):519-20. doi: 10.1136/adc.2006.097493. Epub 2006 Jun 23.

Abstract

We report a case of pneumonia in a 13 month old male child with partial DiGeorge syndrome who died after inadvertently receiving live viral vaccines. Although live viral vaccines have been used safely in some children with DiGeorge syndrome, there are insufficient data to recommend their routine use in those with severe immunodeficiency.

Publication types

  • Case Reports

MeSH terms

  • DiGeorge Syndrome / complications*
  • DiGeorge Syndrome / immunology
  • Fatal Outcome
  • Humans
  • Immunocompromised Host
  • Infant
  • Male
  • Measles-Mumps-Rubella Vaccine / adverse effects
  • Opportunistic Infections / etiology*
  • Opportunistic Infections / immunology
  • Pneumonia, Viral / etiology*
  • Pneumonia, Viral / immunology
  • Viral Vaccines / adverse effects*

Substances

  • Measles-Mumps-Rubella Vaccine
  • Viral Vaccines