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Immunity. 2006 Jun;24(6):663-6.

Why aging T cells fail: implications for vaccination.

Author information

1
Trudeau Institute, Inc., Saranac Lake, New York 12983, USA.

Abstract

The decline in CD4+ T cell function with aging contributes to reduced vaccine efficacy. In this commentary, we discuss the factors leading to age-related changes in T cell function and propose how they may be overcome to enhance vaccine efficacy for the elderly.

PMID:
16782020
DOI:
10.1016/j.immuni.2006.06.003
[Indexed for MEDLINE]
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