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Curr Biol. 2006 Jun 20;16(12):R459-62.

Lambda's switch: lessons from a module swap.

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1
Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA. m-ptashne@mskcc.org

Abstract

A recent experiment has replaced Cro, a crucial component of lambda's genetic switch, with the lac repressor (plus two lac operators). The resulting hybrid phage is viable, but a subtle phenotypic defect explains a puzzle concerning the workings of the switch.

PMID:
16782001
DOI:
10.1016/j.cub.2006.05.037
[Indexed for MEDLINE]
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