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J Membr Biol. 2006 Feb-Mar;209(2-3):89-118. Epub 2006 May 25.

Hair cells--beyond the transducer.

Author information

1
Department of Physiology, University of Auckland, Private Bag, 92019, Auckland, New Zealand. g.housley@auckland.ac.nz

Erratum in

  • J Membr Biol. 2008 Jun;223(3):173.

Abstract

OVERVIEW:

This review considers the "tween twixt and twain" of hair cell physiology, specifically the signaling elements and membrane conductances which underpin forward and reverse transduction at the input stage of hair cell function and neurotransmitter release at the output stage. Other sections of this review series outline the advances which have been made in understanding the molecular physiology of mechanoelectrical transduction and outer hair cell electromotility. Here we outline the contributions of a considerable array of ion channels and receptor signaling pathways that define the biophysical status of the sensory hair cells, contributing to hair cell development and subsequently defining the operational condition of the hair cells across the broad dynamic range of physiological function.

PMID:
16773496
DOI:
10.1007/s00232-005-0835-7
[Indexed for MEDLINE]
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