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Internist (Berl). 2006 Jun;47 Suppl 1:S14-9.

[Pneumonia - pathogen-based or constellation-based therapy?].

[Article in German]

Author information

1
Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charite, Campus Virchow Klinikum, Augustenburger Platz 1, 13 353 Berlin. antje.kuhnke@charite.de

Abstract

Community-acquired pneumonia is one of the most frequent infectious diseases with high morbidity and mortality. Early and sufficient antibiotic treatment is crucial for the prognosis of the patient. The underlying pathogens are mostly unknown at the onset of symptoms. The choice of antibiotic treatment depends on the suspected pathogens, derived from the typical germs and the typical resistances in a certain area. In addition, individual risk factors, such as age, severity of the diseases, comorbidities, and previous antibiotic treatment have a major impact on the probability of dying for an individual patient. These factors must be considered at the beginning of any treatment. Pathogen-based treatment has to be switched to constellation-based treatment.

PMID:
16773362
DOI:
10.1007/s00108-006-1623-x
[Indexed for MEDLINE]

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