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Ophthalmology. 2006 Aug;113(8):1425-31. Epub 2006 Jun 12.

Clinical application of rapid serial fourier-domain optical coherence tomography for macular imaging.

Author information

1
Department of Ophthalmology & Vision Science, University of California-Davis, Sacramento, California 95817, USA.

Abstract

PURPOSE:

To introduce and examine the utility of a retinal imaging technique using high-speed optical coherence tomography (OCT) for creating a more complete retinal structural map to aid in the evaluation of patients with macular pathology.

DESIGN:

Prospective observational case series.

PARTICIPANTS:

Five patients with a variety of macular pathologies.

METHODS:

Patients were imaged with a Fourier-domain high-speed high-resolution OCT system built at our institution. A sweeping serial OCT B-scan of the macula was acquired to create a detailed retinal structural map. The data were then used to make individual clinical observations.

RESULTS:

Rapid serial OCT B-scans produced detailed macular maps for all 5 patients. Diagnoses of imaged patients included macular hole, lamellar macular hole, regressed macular hole or macular microhole, choroidal neovascular membrane (CNV) from age-related macular degeneration, and CNV from presumed ocular histoplasmosis syndrome. Reconstructed B-scans and C-scans are shown for selected patients to illustrate the additional perspectives gained by obtaining a detailed retinal map.

CONCLUSIONS:

Rapid serial Fourier-domain OCT B-scanning can be used to create a detailed retinal structural map. This technique provides additional information that can be missed on single OCT images and provides an accurate way to image large or complex lesions, and allows B-scan and C-scan reconstructions to be made that provide additional perspectives into retinal structures that may be missed using traditional imaging methods.

PMID:
16766031
PMCID:
PMC2586055
DOI:
10.1016/j.ophtha.2006.03.020
[Indexed for MEDLINE]
Free PMC Article

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