Format

Send to

Choose Destination
See comment in PubMed Commons below
Eur Psychiatry. 2006 Jun;21(4):270-3. Epub 2006 Jun 9.

The relationship of impulsivity to response inhibition and decision-making in remitted patients with bipolar disorder.

Author information

  • 1Section of Neurobiology of Psychosis (PO66), Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK.

Abstract

BACKGROUND:

Impulsivity, a core feature of bipolar disorder (BD), is a multifaceted concept encompassing failure of response inhibition and poor decision-making. Abnormalities in these two cognitive domains have been reported in BD patients but their relationship with impulsivity has not been explored.

METHODS:

Twenty-five remitted patients with BD completed the Barratt Impulsiveness Scale (BIS) and performed the Hayling Sentence Completion Task (HSCT) and a computerized version of the Iowa Gambling task. The HSCT total errors scaled score was used as a measure of response inhibition while the gabling task score, which reflects participants' ability to make advantageous choices, was used a measure of decision making.

RESULTS:

Higher scores on the BIS attentional and non-planning subscales were respectively associated with more errors in the HSCT and less advantageous choices in the gambling task.

LIMITATIONS:

All patients were medicated. Healthy participants were not included.

CONCLUSIONS:

Viewed in the context of recent relevant studies our findings suggest that impulsivity, response inhibition and decision-making in BD may represent behavioural manifestations of the same underlying biological mechanism possibly linked to ventral prefrontal cortical function.

PMID:
16762532
DOI:
10.1016/j.eurpsy.2006.04.006
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center