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J Perinatol. 2006 Aug;26(8):498-500. Epub 2006 Jun 8.

Does intensive phototherapy produce hemolysis in newborns of 35 or more weeks gestation?

Author information

1
Department of Pediatrics, William Beaumont Hospital, Royal Oak, MI 48073, USA. jmaisels@beaumont.edu

Abstract

OBJECTIVE:

Because there is some in vivo and in vitro evidence that standard phototherapy might produce hemolysis, we wished to know whether intensive phototherapy produces hemolysis.

STUDY DESIGN:

We measured end-tidal carbon monoxide (CO) concentration corrected for ambient CO (ETCOc) in 27 newborn infants > or =35 weeks gestation receiving intensive phototherapy (average irradiance 43 microW/cm2/nm).

RESULTS:

There was a steady decrease in the mean ETCOc over the course of the phototherapy.

CONCLUSION:

Intensive phototherapy did not produce hemolysis in infants > or =35 weeks gestation.

PMID:
16761009
DOI:
10.1038/sj.jp.7211552
[Indexed for MEDLINE]

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