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Nat Rev Neurosci. 2006 May;7(5):335-46.

The sympathetic control of blood pressure.

Author information

1
Department of Pharmacology, Health Sciences Center, University of Virginia, 1300 Jefferson Park Avenue, Charlottesville, Virginia 22908-0735, USA. pgg@virginia.edu

Abstract

Hypertension - the chronic elevation of blood pressure - is a major human health problem. In most cases, the root cause of the disease remains unknown, but there is mounting evidence that many forms of hypertension are initiated and maintained by an elevated sympathetic tone. This review examines how the sympathetic tone to cardiovascular organs is generated, and discusses how elevated sympathetic tone can contribute to hypertension.

PMID:
16760914
DOI:
10.1038/nrn1902
[Indexed for MEDLINE]
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