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Psychiatr Pol. 2006 Jan-Feb;40(1):129-38.

[Stressful events in childhood and psychiatric disorders in the elderly].

[Article in Polish]

Author information

1
Klinika Psychiatrii Rozwojowej, Zaburzeń Psychotycznych i Wieku Podeszłego AM w Gdańsku.

Abstract

Neurotrophins have been implicated in the regulation of development, neuronal survival, and adult synaptic plasticity. Brain-derived neurotrophic factor (BDNF) plays an important role in development, synapse remodelling and responses to stress and injury. Its abnormal expression has been implicated in many neuropsychiatric disorders. Adverse life events occurring early in development may alter the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus and other brain areas and render the organism more vulnerable to psychiatric disorders.

PMID:
16756035
[Indexed for MEDLINE]
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