Objective: To evaluate the expression and significance of 16S rDNA in prostatic secretions (EPS) of chronic prostatitis.
Methods: 16S rDNA was detected in EPS of 116 patients with chronic prostatitis by PCR.
Results: 16S rDNA were positively expressed in all 29 cases of II type chronic bacterial prostatitis and 71 out of 87 cases of III type chronic prostatitis (82%). The positive rates were 94% (45/48) and 67% (26/39) in lIIA and IIIB chronic prostatitis respectively. There was a statistical difference in 16S rDNA positive rate between IIIA and IlB chronic prostatitis (P < 0.01).
Conclusion: Detection of 16s rDNA may be a useful index for the diagnosis and classification of chronic prostatitis.