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Cell. 2006 Jun 2;125(5):840-2.

Bone formation: The nuclear matrix reloaded.

Author information

1
Stowers Institute for Medical Research, 1000 50(th) Street, Kansas City, MO 64110, USA.

Abstract

In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matrix protein Satb2 represses Hoxa2 expression and acts with other regulatory proteins to promote osteoblast differentiation. This work suggests a molecular mechanism that enables the integration of patterning and differentiation during bone formation.

PMID:
16751095
DOI:
10.1016/j.cell.2006.05.022
[Indexed for MEDLINE]
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