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Biochim Biophys Acta. 2006 May-Jun;1763(5-6):442-9. Epub 2006 Apr 20.

Mitochondrial dynamics and Ca2+ signaling.

Author information

1
Department of Experimental and Diagnostic Medicine and Interdisciplinary Center for the Study of Inflammation and ER-GenTech, University of Ferrara, Italy.

Abstract

Recent data shed light on two novel aspects of the mitochondria-Ca2+ liaison. First, it was extensively investigated how Ca2+ handling is controlled by mitochondrial shape, and positioning; a playground also of cell death and survival regulation. On the other hand, significant progress has been made to explore how intra- and near-mitochondrial Ca2+ signals modify mitochondrial morphology and cellular distribution. Here, we shortly summarize these advances and provide a model of Ca2+-mitochondria interactions.

PMID:
16750865
DOI:
10.1016/j.bbamcr.2006.04.002
[Indexed for MEDLINE]
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