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Laryngoscope. 2006 Jun;116(6):966-9.

Treatment of ranula in pediatric patients with intralesional injection of OK-432.

Author information

1
Department of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.

Abstract

OBJECTIVE:

To assess the efficacy of treatment of a ranula in children by intralesional injection of OK-432.

STUDY DESIGN:

Retrospective analysis of 13 cases.

METHODS:

Review of medical records of pediatric patients with ranula treated by OK-432 sclerotherapy from 2002 through 2005.

RESULTS:

Among 13 cases, 9 were completely regressed by injection therapy alone. Three cases were incompletely regressed. One case was cured by surgical excision. The follow-up duration was 6 to 46 (mean 24.3) months. Adverse effects of OK-432 injection were tolerable, and no complication was observed.

CONCLUSIONS:

On the basis of our experience, sclerotherapy with OK-432 was a safe and effective primary treatment for a ranula in children. Further study will be needed to conclude its long-term effectiveness.

[Indexed for MEDLINE]

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