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Adv Parasitol. 2006;61:223-74.

Chemotherapy in the treatment and control of leishmaniasis.

Author information

1
Department for Control of Neglected Tropical Diseases, World Health Organization, 20 Avenue Appia CH-1211 Geneva 27, Switzerland.

Abstract

Drugs remain the most important tool for the treatment and control of both visceral and cutaneous leishmaniasis. Although there have been several advances in the past decade, with the introduction of new therapies by liposomal amphotericin, oral miltefosine and paromomycin (PM), these are not ideal drugs, and improved shorter duration, less toxic and cheaper therapies are required. Treatments for complex forms of leishmaniasis and HIV co-infections are inadequate. In addition, full deployment of drugs in treatment and control requires defined strategies, which can also prevent or delay the development of drug resistance.

PMID:
16735166
DOI:
10.1016/S0065-308X(05)61006-8
[Indexed for MEDLINE]

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