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J Neuroradiol. 2006 Apr;33(2):126-8.

Diffusion weighted imaging of cerebellar lesions in Wernicke's encephalopathy.

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Department of Neurology and Stroke Center, Bichat University Hospital and Medical School, Paris.


We report unusual findings on MR imaging in a 62-year-old woman with Wernicke's encephalopathy (WE). Initial fluid-attenuated inversion recovery (FLAIR) and diffusion weighted MR imaging (DW-MRI) showed hyperintense lesions in the cerebellum and medial thalami, with a decreased apparent diffusion coefficient (ADC) in the cerebellum (reduced by 45%). After thiamine supplementation, the T2 and diffusion hyperintensities disappeared. However, clinical examination at three months showed persistent cerebellar impairment. The importance of the ADC values should be further investigated.

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