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Pediatr Infect Dis J. 2006 Jun;25(6):559-60.

Childhood empyema: limited potential impact of 7-valent pneumococcal conjugate vaccine.

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Faculty of Health and Social Care, University of the West of England, Bristol, UK.


During 2003-2004, locally presenting pleural empyema cases in children increased 3-fold. Antigen analysis of empyema fluid identified Streptococcus pneumoniae in 27 of 29 cases for whom samples were available and capsular polysaccharide type 1 in 18 of these. Use of a conjugate vaccine without serotype 1 antigen would have had limited impact on this morbidity in our region.

[Indexed for MEDLINE]

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