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Radiother Oncol. 2006 Jun;79(3):298-303. Epub 2006 May 26.

A dosimetric analysis of interstitial intensity modulated implants for pelvic recurrences, base of tongue and orbita tumors with specific references to the ICRU-58.

Author information

1
Clinic of Radiotherapy, University Hospital of Schleswig-Holstein, Kiel, Germany. siebert@onco.uni-kiel.de

Abstract

BACKGROUND AND PURPOSE:

In this article the conversion of the dosimetry of three different kinds of IMBT (intensity modulated brachytherapy) implants into ICRU-58 formalism is presented. The results allow an inter-study comparison of relative reference doses between different sites.

PATIENTS AND METHODS:

The evaluation included 76 patient plans: (a) 31 pelvic recurrences, (b) 30 base of tongue tumors, and (c) 15 orbita tumors were analysed retrospectively and the mean central doses (MCD) and relative reference doses were evaluated.

RESULTS:

The reference doses D(ref) normalized to the mean central doses of three subgroups resulted in (a) 66%, (b) 68%, and (c) 52%. This is in contrast to the generally proposed standard reference dose of 85% of the Paris system.

CONCLUSIONS:

Reduction of the reference dose yields to higher dose inhomogeneities and affects the positive local tumor control. It was found that in IMBT implants the 85% reference dose of the Paris system is suitable for reporting purposes but not necessarily for dose prescription. Consequently, in IMBT implants the prescription dose of 85% should be critically used.

PMID:
16730084
DOI:
10.1016/j.radonc.2006.04.013
[Indexed for MEDLINE]
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