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J Nat Prod. 2006 May;69(5):731-5.

Bromophycolides C-I from the Fijian red alga Callophycus serratus.

Author information

1
School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332, USA. julia.kubanek@biology.gatech.edu

Abstract

Bromophycolides C-I (1-7) were isolated from extracts of the Fijian red alga Callophycus serratus and identified by NMR and mass spectral techniques. These novel natural products share a carbon skeleton and biosynthetic origin with previously identified bromophycolides A (8) and B (9), which form a rare group of diterpene-benzoate macrolides. Bromophycolides C-I (1-7) displayed modest antineoplastic activity against a range of human tumor cell lines.

PMID:
16724831
PMCID:
PMC2528861
DOI:
10.1021/np050463o
[Indexed for MEDLINE]
Free PMC Article

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