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Nat Rev Mol Cell Biol. 2006 Aug;7(8):617-22. Epub 2006 May 24.

Proteome chips for whole-organism assays.

Author information

1
Department of Molecular, Cellular and Developmental Biology, Yale University, 266 Whitney Avenue, New Haven, Connecticut 06511, USA. li.kung@yale.edu

Abstract

Over the past 5 years, protein-chip technology has emerged as a useful tool for the study of many kinds of protein interactions and biochemical activities. The construction of Saccharomyces cerevisiae whole-proteome arrays has enabled further studies of such interactions in a proteome-wide context. Here, we explore some of the recent advances that have been made at the '-omic' level using protein microarrays.

PMID:
16723973
DOI:
10.1038/nrm1941
[Indexed for MEDLINE]
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