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Antimicrob Agents Chemother. 2006 Jun;50(6):2248-50.

In vitro activities of 10 combinations of antifungal agents against the multiresistant pathogen Scopulariopsis brevicaulis.

Author information

1
Servicio de MicologĂ­a, Centro Nacional de MicrobiologĂ­a, Instituto de Salud Carlos III, Majadahonda (Madrid), Spain. mcuenca-estrella@isciii.es

Abstract

The activities of 10 combinations of antifungal agents against 25 clinical isolates of Scopulariopsis brevicaulis were tested by the checkerboard technique. An average indifferent effect was detected for all combinations. Synergy was observed for some isolates and combinations, particularly with posaconazole-terbinafine (68% of strains), amphotericin B-caspofungin (60%), and posaconazole-caspofungin (48%).

PMID:
16723597
PMCID:
PMC1479145
DOI:
10.1128/AAC.00162-06
[Indexed for MEDLINE]
Free PMC Article

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