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Acta Paediatr. 2006 Apr;95(4):502-4.

Endogenous ethanol fermentation in a child with short bowel syndrome.

Author information

1
Section of Infectious Diseases, Department of Medical Sciences, University Hospital, Uppsala, Sweden.

Abstract

The term "auto-brewery syndrome" has been frequently used to describe patients who show features of alcohol intoxication because of abnormal yeast proliferation after ingesting carbohydrate-rich meals. We present a case of a 3-y-old girl with short bowel syndrome (SBS) who demonstrated signs of alcohol intoxication on repeated occasions. A blood test indicated an ethanol concentration of 15 mmol/l, and cultures from gastric fluid and faeces showed the presence of Candida kefyr. An association was found between the introduction of a carbohydrate-rich fruit drink and the occurrence of symptoms.

CONCLUSION:

The possibility of endogenous ethanol fermentation should be considered in patients with SBS and the diagnosis of auto-brewery syndrome added to the differential diagnosis list for D-lactic acidosis. Management includes both antifungal treatment and special diet modification.

PMID:
16720504
DOI:
10.1080/08035250500501625
[Indexed for MEDLINE]

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