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Nat Prod Res. 2006 Apr;20(4):335-9.

Xanthine oxidase inhibiting flavonol glycoside from Amberboa ramosa.

Author information

  • 1International Centre for Chemical Sciences, HEJ Research Institute of Chemistry, University of Karachi, Pakistan.

Abstract

A new flavonol glycoside (1) has been isolated from the ethyl acetate soluble fraction of Amberboa ramosa and assigned the structure 5,7,4'-trihydroxy-3,8-dimethoxylflavone 5-O-beta-D-gluco-pyranoside (1). In addition, 6,4'-dihydroxy-3,5,7-trimethoxyflavone (2), 5,7-dihydroxy-4'-methoxyflavone (3) and (23R)-5alpha-cycloart-24-ene-3beta,21,23-triol (4) have also been reported for the first time from this species. The structures were deduced on the basis of 1D and 2D NMR techniques. The compounds 1-3 displayed weak to moderate inhibition against the xanthine oxidase enzyme.

PMID:
16715589
DOI:
10.1080/14786410500182110
[PubMed - indexed for MEDLINE]
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