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Bioelectrochemistry. 2007 Jan;70(1):122-6. Epub 2006 Apr 5.

Conformational change of membrane proteins leads to shape changes of red blood cells.

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1
Laboratory of Biophysics, Saarland University, P.O. Box 151150, 66041 Saarbrücken, Germany.

Abstract

High-resolution atomic force microscopy (AFM) allows a new insight into the surface of mammalian cells. Using the human red blood cell (RBC) as a model, we have demonstrated an important correlation between the conformation of membrane proteins measured from the external face of the cell and the cell shape.

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