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Emerg Infect Dis. 2006 Jun;12(6):958-62.

Coccidioidomycosis as a common cause of community-acquired pneumonia.

Author information

1
University of Arizona College of Medicine, Tucson, Arizona 85723, USA.

Erratum in

  • Emerg Infect Dis. 2006 Aug;12(8):1307.

Abstract

The early manifestations of coccidioidomycosis (valley fever) are similar to those of other causes of community-acquired pneumonia (CAP). Without specific etiologic testing, the true frequency of valley fever may be underestimated by public health statistics. Therefore, we conducted a prospective observational study of adults with recent onset of a lower respiratory tract syndrome. Valley fever was serologically confirmed in 16 (29%) of 55 persons (95% confidence interval 16%-44%). Antimicrobial medications were used in 81% of persons with valley fever. Symptomatic differences at the time of enrollment had insufficient predictive value for valley fever to guide clinicians without specific laboratory tests. Thus, valley fever is a common cause of CAP after exposure in a disease-endemic region. If CAP develops in persons who travel or reside in Coccidioides-endemic regions, diagnostic evaluation should routinely include laboratory evaluation for this organism.

PMID:
16707052
PMCID:
PMC3373055
[Indexed for MEDLINE]
Free PMC Article

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