Fatal cor pulmonale caused by pulmonary tumor microembolism in a patient with occult gastric cancer

Cardiovasc Pathol. 2006 May-Jun;15(3):157-60. doi: 10.1016/j.carpath.2006.02.003.

Abstract

Background: A fatal pulmonary tumor microembolism is rarely caused by an occult gastric cancer.

Methods and results: We report the case of a 40-year-old woman who died after 3 days of progressive dyspnea, cough, and pulmonary hypertension. Postmortem examination demonstrated the presence of an occult diffuse-type gastric carcinoma, which had caused emboli in about 80% of small pulmonary arteries and arterioles. Despite an interatrial defect in the fossa ovalis, no parenchymal metastases were documented.

Conclusion: Pulmonary tumor microembolism may be suspected in patients complaining of unexplained progressive dyspnea and who develop acute or subacute cor pulmonale.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma, Signet Ring Cell / complications*
  • Carcinoma, Signet Ring Cell / pathology
  • Fatal Outcome
  • Female
  • Humans
  • Lung / diagnostic imaging
  • Lung / pathology
  • Lymphatic Metastasis
  • Pulmonary Embolism / diagnostic imaging
  • Pulmonary Embolism / etiology*
  • Pulmonary Embolism / pathology
  • Pulmonary Heart Disease / etiology*
  • Stomach Neoplasms / complications*
  • Stomach Neoplasms / pathology
  • Tomography, X-Ray Computed