Send to

Choose Destination
See comment in PubMed Commons below

Cellular immunity in splenectomized patients.

Author information

  • 1Department of Biopathology, La Fe Hospital, Valencia, Spain.


Delayed hypersensitivity and lymphocyte subsets in a group of adult splenectomized patients after abdominal trauma without associated disease have been studied. The results were compared with those observed in healthy individuals. The results show a decreased cutaneous reaction against extracts of Streptococcus and diphtheria antigens. Moreover, an increase in the number of lymphocytes and monocytes was observed, but the T4/T8 ratio was not affected. The impaired cutaneous response against Streptococcus could be related to post-splenectomy sepsis.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center