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Genome Biol. 2006;7(5):217. Epub 2006 May 10.

Histone H4 lysine 16 acetylation breaks the genome's silence.

Author information

1
Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA.

Abstract

Acetylation at histone H4 lysine 16 is involved in many cellular processes in organisms as diverse as yeast and humans. A recent biochemical study pinpoints this particular acetylation mark as a switch for changing chromatin from a repressive to a transcriptionally active state.

PMID:
16689998
PMCID:
PMC1779524
DOI:
10.1186/gb-2006-7-5-217
[Indexed for MEDLINE]
Free PMC Article

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