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J Occup Environ Med. 2006 May;48(5):455-61.

Long-term longitudinal study on the relationship between alternating shift work and the onset of diabetes mellitus in male Japanese workers.

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1
Department of Occupational and Environmental Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan. suwa@faculty.chiba-u.jp

Abstract

OBJECTIVE:

This study investigated the effect of alternating shift work (ASW) on the onset of diabetes mellitus in Japanese workers compared with onset in day-shift work (DSW).

METHODS:

A longitudinal study was carried out on a DSW group (n = 3203) and ASW group (n = 2426) of a steel company who received their annual health checkups over a 10-year period between 1991 and 2001. The association between job schedule type and onset of diabetes mellitus (glycated hemoglobin A1c > or =6.0% or medication) was investigated by multivariate pooled logistic regression analyses.

RESULTS:

The odds ratio (95% confidence interval) for the development of diabetes mellitus in the ASW group compared with the DSW group was 1.35 (1.05-1.75).

CONCLUSIONS:

Our study revealed that the ASW is an independent risk factor for the onset of diabetes mellitus.

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