Send to

Choose Destination
Trends Genet. 1991 Nov-Dec;7(11-12):403-8.

Choosing a cell fate: a view from the Notch locus.

Author information

Howard Hughes Medical Institute, Department of Cell Biology, Yale University, New Haven, CT 06511.


During the development of Drosophila melanogaster, individual cells must make choices between a restricted set of possible fates in order to give rise to spatial patterns composed of different types of differentiated cells. The Notch locus appears to play a central and general role in the regulative events that control the local architecture of the final cellular pattern in several tissues, among them being the central and peripheral nervous systems.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center