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Curr Opin Cell Biol. 1991 Dec;3(6):1025-32.

ERKs, extracellular signal-regulated MAP-2 kinases.

Author information

1
University of Texas Southwestern Medical Center, Dallas.

Abstract

A family of protein kinases, known alternatively as microtubule-associated protein-2/myelin basic protein kinases or extracellular signal-regulated kinases, is activated by numerous hormones, growth factors and other extracellular stimuli. At least two members of this family function as intermediate kinases in protein phosphorylation cascades. Their mechanisms of activation may involve autophosphorylation, which occurs on both threonine and tyrosine residues.

PMID:
1667578
DOI:
10.1016/0955-0674(91)90124-h
[Indexed for MEDLINE]

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