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Curr Opin Microbiol. 2006 Jun;9(3):245-51. Epub 2006 May 3.

Discovery of novel metabolites from marine actinomycetes.

Author information

1
Department of Microbiology and Anti-infective Discovery, Nereus Pharmaceuticals, Inc., 10480 Wateridge Circle, San Diego, CA 92121, USA. rlam@nereuspharm.com

Abstract

Recent findings from culture-dependent and culture-independent methods have demonstrated that indigenous marine actinomycetes exist in the oceans and are widely distributed in different marine ecosystems. There is tremendous diversity and novelty among the marine actinomycetes present in marine environments. Progress has been made to isolate novel actinomycetes from samples collected at different marine environments and habitats. These marine actinomycetes produce different types of new secondary metabolites. Many of these metabolites possess biological activities and have the potential to be developed as therapeutic agents. Marine actinomycetes are a prolific but underexploited source for the discovery of novel secondary metabolites.

PMID:
16675289
DOI:
10.1016/j.mib.2006.03.004
[Indexed for MEDLINE]

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