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Beilstein J Org Chem. 2006 May 4;2:9.

The oxanorbornene approach to 3-hydroxy, 3,4-dihydroxy and 3,4,5-trihydroxy derivatives of 2-aminocyclohexanecarboxylic acid.

Author information

  • 1Department of Chemistry, University of Durham, South Road, Durham, DH1 3LE, UK. masesane@mopipi.ub.bw

Abstract

The nitro oxanorbornene adduct derived from the Diels-Alder reaction of ethyl (E)-3-nitroacrylate and furan provides a versatile template for the stereoselective synthesis of hydroxylated derivatives of 2-aminocyclohexanecarboxylic acid (ACHC).

PMID:
16674802
PMCID:
PMC1524792
DOI:
10.1186/1860-5397-2-9
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