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Am J Obstet Gynecol. 2006 May;194(5):e20-2. Epub 2006 Apr 21.

Retrospective cohort study of surgical staging for ovarian low malignant potential tumors.

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1
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9032, USA.

Abstract

OBJECTIVE:

The purpose of this study was to determine the benefit of surgically staging ovarian low malignant potential tumors.

STUDY DESIGN:

This was a retrospective cohort study of all ovarian low malignant potential tumors that were diagnosed by frozen section or final pathologic review from 2003 to 2005.

RESULTS:

Twenty-two of 32 patients (69%) were staged surgically. Sixteen low malignant potential tumors were stage I by final pathologic review, and 4 tumors were upstaged to stage II-III disease. Two other patients had early invasive ovarian carcinoma, despite a frozen section that suggested low malignant potential; 1 patient received adjuvant chemotherapy. The tumors of 10 women (31%) were unstaged. Frozen section suspicion of low malignant potential (P = .003) and surgery by a gynecologic oncologist (P < .001) correlated with staging. Preoperative CA-125, intraoperative blood loss, and postoperative hospitalization were increased in patients with staged disease (each P < .05). Two women who underwent fertility-sparing surgery experienced a recurrence in the contralateral ovary.

CONCLUSION:

Surgical staging of ovarian low malignant potential tumors has limited value for most patients, unless invasive carcinoma is diagnosed by final pathologic review.

PMID:
16647891
DOI:
10.1016/j.ajog.2005.11.033
[Indexed for MEDLINE]
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