Format

Send to

Choose Destination
See comment in PubMed Commons below
Antimicrob Agents Chemother. 2006 May;50(5):1852-4.

Nebulized amphotericin B combined with intravenous amphotericin B in rats with severe invasive pulmonary aspergillosis.

Author information

1
Department of Clinical Pharmacy, Medical Center Rijnmond-Zuid, Olympiaweg 350, 3078 HT Rotterdam, The Netherlands. e.j.ruijgrok@hetnet.nl

Abstract

Nebulized amphotericin B (AMB) combined with intravenous AMB was studied in persistently leukopenic rats with invasive pulmonary aspergillosis. Pulmonary concentrations of AMB after aerosol treatment were substantially higher than after intravenous liposomal AMB. Nebulized liposomal AMB in addition to intravenous AMB resulted in significantly prolonged survival compared to controls.

PMID:
16641459
PMCID:
PMC1472188
DOI:
10.1128/AAC.50.5.1852-1854.2006
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center