Basic method of treating diskogenic radiculopathy is surgical treatment, aim of which is to remove the disk hernia and the root compression. Traditional methods of therapy are of temporary character. The aim of our study was to search for alternative methods of treatment of diskogenic radiculopathy using glukosamin sulfate and chondroitin sulfate. 6 patients have been examined with the aid of clinical characteristics and spinal MRI, a diagnosis of lumbar diskopathy was stated. Treatment was carried out using glukosamin sulfate and chondroitin sulfate according to specific scheme. The paper includes two cases as illustrations. The observations carried out on the patients showed that a long-term usage of glukosamin sulfate and chondroitin sulfate can serve as an alternative way of treating the diskogenic radiculopathy at least in some cases. On the other hand, it should be supposed that as a long-term course treatment with the glukosamin and chondroitin improves metabolism of cartilageous tissues and it can serve as a prevention measure for the reappearance of the pathological process.