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Neurology. 2006 Apr 25;66(8):1270-2.

Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex.

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Division of Pediatric Neurology, The Brain Research Institute, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.


The authors assessed whether magnetoencephalography/magnetic source imaging (MEG/MSI) identified epileptogenic zones in patients with tuberous sclerosis complex (TSC). In six TSC children with focal seizures, ictal video-EEG predicted the region of resection with 56% sensitivity, 80% specificity, and 77% accuracy (p = 0.02), whereas interictal MEG/MSI fared better (100%, 94%, and 95%, respectively; p < 0.0001). Interictal MEG/MSI seems to identify epileptogenic zones more accurately in children with TSC and focal intractable epilepsy.

[Indexed for MEDLINE]

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