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Alcohol Alcohol. 2006 Jul-Aug;41(4):358-63. Epub 2006 Apr 24.

Liver transplantation for alcoholic liver disease: a systematic review of psychosocial selection criteria.

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1
Department of Psychiatry, Queen Margaret Hospital, Whitefield Road, Dunfermline, Fife KY12 0RG, Scotland. seonaid.mccallum@faht.scot.nhs.uk

Abstract

AIMS:

To examine the evidence base for psychosocial selection criteria for liver transplant candidates with alcoholic liver disease.

METHOD:

Systematic review using three electronic databases supplemented by hand searches.

RESULTS:

Out of 96 published studies, 22 were included. All but one were cohort design, most were retrospective, single centre, and small sample. Methodology varied considerably, such that meta-analysis was not feasible.

CONCLUSIONS:

Social stability, no close relatives with an alcohol problem, older age, no repeated alcohol-treatment failures, good compliance with medical care, no current polydrug misuse, and no co-existing severe mental disorder have all been associated with future abstinence in more studies than not, in those that examined these variables. Duration of preoperative abstinence was a poor predictor. We recommend that, if predicting future abstinence is considered necessary by transplant teams, a standardized approach is agreed and deployed amongst transplant units, then audited and reviewed.

PMID:
16636009
DOI:
10.1093/alcalc/agl033
[Indexed for MEDLINE]
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