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Ginecol Obstet Mex. 2006 Jan;74(1):20-8.

[Endometriosis and deficient intake of antioxidants molecules related to peripheral and peritoneal oxidative stress].

[Article in Spanish]

Author information

1
Departamento de Ultramicroscopía, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Lomas Virreyes, México, DF. hehecatlzin@yahoo.com

Abstract

OBJECTIVE:

To evaluate the antioxidant intake and the lipoperoxidation status in plasma and peritoneal fluid of women with endometriosis.

PATIENTS AND METHODS:

The study was carried out in 48 women with endometriosis obtained at the Sterility Clinic from the National Institute of Perinatology. The antioxidant intake was evaluated applying the Questionnaire Assessment of Antioxidants and Retinol Intakes in Mexican women validated by the National Institute of Public Health. The lipoperoxidation status was determined in plasma and peritoneal fluid with the malondyaldehyde method. Results were analyzed by ANOVA of Kruskal-Wallis.

RESULTS:

The antioxidant intake (vitamin C, vitamin E, selenium and zinc) of women with endometriosis showed a significative statistical difference when data was compared with the control group, including total group and those stratified in pathology stages. The lipoperoxidation status in plasma and peritoneal fluid of women with endometriosis, analyzed in group, did not show statistical difference versus healthy women. When data was stratified according to the pathology severity, the percentage of lipoperoxidation status increased in plasma in the severe grade of endometriosis and in peritoneal fluid in the moderate and severe grades.

CONCLUSIONS:

The antioxidant intake in women with endometriosis showed an inverse correlation with the pathology intensity. As endometriosis severity intensifies, a less intake of antioxidants is present. There is a positive association between the pathology development and the lipoperoxidation status.

PMID:
16634350
[Indexed for MEDLINE]

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