Format

Send to

Choose Destination
Neuron. 2006 Apr 20;50(2):175-7.

Nob mice wave goodbye to eye-specific segregation.

Author information

1
Department of Neurobiology, Stanford University School of Medicine, Palo Alto, California 94305, USA.

Abstract

Spontaneous retinal activity is necessary to establish and maintain eye-specific projections to the LGN, but whether the spatial and temporal structure of this activity is important remains unclear. A new study by Demas et al. in the current issue of Neuron shows that when the frequency of spontaneous retinal waves is increased and waves abnormally persist past eye opening, eye-specific projections to the LGN desegregate. These results provide important new insight into the mechanisms that drive eye-specific refinement and stabilization.

PMID:
16630826
DOI:
10.1016/j.neuron.2006.04.006
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center