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Cell. 2006 Apr 21;125(2):224-6.

When a motor goes bad: a kinesin regulates neuronal survival.

Author information

1
Cancer Research and Developmental Biology, Hospital for Sick Children Research Institute, Department of Molecular, University of Toronto, Ontario, Canada M5G 1X8. dkaplan@sickkids.ca

Abstract

In this issue of Cell, Midorikawa et al. (2006) demonstrate that the kinesin superfamily member KIF4, a microtubule-based molecular motor, regulates the survival of electrically active neurons in the developing brain by modulating the function of poly(ADP-ribose) polymerase-1 in an unexpected way.

PMID:
16630809
DOI:
10.1016/j.cell.2006.03.031
[Indexed for MEDLINE]
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