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Cell. 2006 Apr 21;125(2):219-21.

Bent out of shape: RNA unwinding by the DEAD-box helicase Vasa.

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1
Department of Microbiology and Molecular Medicine, Centre Médical Universitaire, University of Geneva, CH-1211 Genève 4, Switzerland. patrick.linder@medecine.unige.ch

Abstract

RNA helicases of the DEAD-box family are involved in essentially all RNA-dependent cellular processes. In this issue of Cell, Sengoku et al. (2006) solve the structure of the DEAD-box protein Vasa in the presence of RNA and a nonhydrolyzable ATP analog and provide important insights into how this family of helicases unwinds RNA.

PMID:
16630807
DOI:
10.1016/j.cell.2006.03.030
[Indexed for MEDLINE]
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