Format

Send to

Choose Destination
See comment in PubMed Commons below
Clin Gastroenterol Hepatol. 2006 May;4(5):635-8.

Hereditary fructose intolerance and celiac disease: a novel genetic association.

Author information

1
Dipartimento di Medicina Clinica e Sperimentale, Università di Napoli Federico II, Napoli, Italy.

Abstract

BACKGROUND & AIMS:

Celiac disease (CD) has been associated with several genetic disorders, but has not been associated with hereditary fructose intolerance (HFI).

METHODS:

We identified CD in 4 female patients affected by HFI from among 38 Italian HFI patients.

RESULTS:

Three of these patients were children in whom the CD-associated signs were hypertransaminasemia, failure to thrive, low weight, and short stature, whereas the adult patient had protracted diarrhea notwithstanding a fructose-free diet. The incidence of CD in our group of HFI patients was higher (>10%) than in the general population (1%-3%) (P<.02).

CONCLUSIONS:

The possibility of an association between these 2 gastrointestinal disorders is important, particularly in the management of HFI patients with persisting symptoms.

PMID:
16630753
DOI:
10.1016/j.cgh.2005.12.004
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center